CONDITIONING OR COGNITION? UNDERSTANDING INTERSPECIFIC COMMUNICATION AS A WAY OF IMPROVING ANIMAL TRAINING (A CASE STUDY WITH ELEPHANTS IN NEPAL)

Conditioning or cognition? Understanding interspecific communication as a way of improving animal training (a case study with elephants in Nepal)

When animals are trained to function in a human society (for example, pet dogs, police dogs, or sports horses), different trainers and training cultures vary widely in their ability to understand how the animal perceives the communication efforts Pumps Air of the trainer.This variation has considerable impact on the resulting performance and welfar

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Expression and Function of Transmembrane-4 Superfamily (Tetraspanin) Proteins in Osteoclasts: Reciprocal Roles of Tspan-5 and NET-6 during Osteoclastogenesis

Background: Osteoclasts are bone-resorbing multinuclear polykaryons essential for bone remodeling, formed through cell fusion of mononuclear macrophage/monocyte lineage precursor cells upon stimulation by the RANK/RANKL system.Recent studies have revealed that a family of tetraspanin proteins, such as CD9, is critically involved in the cell fusion/

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Autophagy dictates sensitivity to PRMT5 inhibitor in breast cancer

Aromatherapy Abstract Protein arginine methyltransferase 5 (PRMT5) catalyzes mono-methylation and symmetric di-methylation on arginine residues and has emerged as a potential antitumor target with inhibitors being tested in clinical trials.However, it remains unknown how the efficacy of PRMT5 inhibitors is regulated.Here we report that autophagy bl

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